Motivated by swampland conjectures, we study the stability of AdS type II supergravity vacua. In the literature, vacuum decay mediated by abelian D-branes has been discussed extensively, while this isn't quite the case for both the D-brane bound states, and their non-abelian counterparts. In this context, we first present a tool to study large classes of D-branes and bound states, based on calibration theory, and then discuss vacuum decay mediated by weakly non-abelian D-branes. We illustrate our results by applying them to a few concrete AdS vacua.